THE SHACK-UP INN

Your second stay in the Delta should be at the Shack-Up Inn in Clarksdale, MS.  It's an entire compound of row houses (I think made to look like the real thing, unlike Tallahatchie Flats, which are the real thing) plus a cotton gin with rooms in it.  We opted for the cotton gin.

Nice modern rooms, with your own porch and rocker.   This is a neat place.  They'll give you a guitar for your stay if you want one.  They often have "harmonica schools" and live music going on.

There's so much old tin and rusty implements around there that they don't allow children!   How awesome is that?

You don't even need to leave to eat.   They have their own restaurant there, fittingly called "Rust", that serves great "Mississippi food with a twist".   We went for the shrimp grits and blackened Mississippi catfish tacos.   Great.